PKD2 / Polycystic kidney disease type 2 (PKD2-related) - Siberian cat

PKD2 / polycystic kidney disease type 2 in Siberian cats

This genetic test examines the PKD2 variant c.2211delG. The condition is also known as PKD2, polycystic kidney disease type 2, PKD in Siberian cats. Affected cats can develop kidney cysts, with pressure on healthy kidney tissue and progressive loss of kidney function. Signs can appear in adulthood and include increased drinking and urination, reduced appetite, vomiting, lethargy and kidney failure.

What is tested?

• The gene: PKD2.
• The variant: c.2211delG.
• The inheritance pattern: autosomal dominant.
• The scope: Siberian cats.

Practical value of this test

The result shows whether a Siberian cat carries the tested PKD2 variant. This helps breeders manage PKD2 deliberately within lines and helps owners recognise and follow cats with genetically increased risk early.