Turnaround time
10 workdays
48.4
40
DNA test for Polycystic kidney disease (PKD) in cats, with analysis of PKD1.

Overview
This genetic test assesses the PKD1 c.9882C>A variant associated with Polycystic kidney disease (PKD) in cats.
PKD involves the development of fluid-filled cysts in the kidneys, which can lead to progressive loss of kidney function over time.
The result helps clarify whether the cat carries this variant. This supports breeding decisions and can contribute to earlier follow-up in cats from at-risk lines.
The trait follows autosomal dominant inheritance.
Included subanalyses
This analysis includes the following subanalysis:
Allele combinations & result interpretations
Below, for each tested locus, you will find the possible allele combinations that may be reported within this analysis, together with a brief explanation of their genetic meaning. The interpretation of possible interactions between different loci is included in the report, but is not shown here in full because that would lead to too many combinations on this page. The final expression may also depend on other genes and their interaction.
Allele combination: No tested PKD1 variant detected
This cat does not carry the tested PKD1 variant. This result supports that this specific variant is not contributing to PKD in this cat.
Allele combination: One copy of the tested PKD1 variant detected
This cat carries one copy of the tested PKD1 variant. Because PKD follows autosomal dominant inheritance, one copy is already relevant and this result fits genetic susceptibility to PKD.
Allele combination: Two copies of the tested PKD1 variant detected
This cat has two copies of the tested PKD1 variant. Available sources describe this outcome as likely homozygous lethal, so living homozygous animals are not or hardly expected.
References