DNA & genetic tests
Pricing
Incl. VAT

48.4

Excl. VAT

40

Night blindness / Appaloosa pattern / Leopard complex (TRPM1-related) - Horse

DNA test for the TRPM1-related LP allele that produces Appaloosa/leopard complex patterning and causes CSNB in LP/LP horses.

Turnaround time
10 workdays
test Methods
Sequencing
Test code
PVT-662794D6E512
Species
Horse
Breeds
American Miniature Horse, Appaloosa, British Spotted Pony, Spotted Pony, United Kingdom of Great Britain and Northern Ireland, Knabstrupper, Miniature Horse, Noric, Pony Of the Americas, Germany
Matrices
Blood, Blood (EDTA), Blood (Heparin), Hair, Semen, Swab, Tissue

Overview

Night blindness and Appaloosa patterning

This genetic test detects the TRPM1-related LP allele for the Appaloosa pattern, also known as leopard complex, leopard spotting or LP. This allele influences the typical white coat patterning, mottled skin, striped hooves and visible sclera seen in Appaloosa-like coat patterns.

The LP allele acts as incomplete dominant for coat patterning: one copy can already produce leopard complex traits. Horses with two copies usually show stronger pattern expression and also develop congenital stationary night blindness, abbreviated CSNB. CSNB reduces vision in dim light and darkness from a young age.

Practical value of this test

  • N/N: no LP allele detected.
  • N/LP: one copy of LP; the horse can show Appaloosa/leopard complex traits and pass the allele on.
  • LP/LP: two copies of LP; this genotype causes CSNB and usually gives clear LP pattern expression.

The result helps breeders plan Appaloosa patterning deliberately while managing the risk of LP/LP offspring with night blindness.

Included subanalyses

This analysis includes the following subanalysis:

  • Night blindness / Appaloosa pattern / Leopard complex (TRPM1-related) - Horse

Allele combinations & result interpretations

Sampling and submission guidelines

References