Turnaround time
10 workdays
48.4
40
DNA test for the RYR1 c.7360C>G variant that causes susceptibility to malignant hyperthermia in horses.
Overview
This genetic test detects the RYR1 variant c.7360C>G for malignant hyperthermia, abbreviated MH. Malignant hyperthermia is an inherited susceptibility in which muscle cells release too much calcium after specific triggers.
In susceptible horses, an episode can be triggered by anesthesia, stress, exercise or other challenging conditions. Episodes can progress rapidly with muscle rigidity, high body temperature, fast heart rate, breathing problems, acidosis and muscle breakdown.
The result is valuable for breeding selection and for identifying horses whose anesthesia and stress management should be planned with extra care.
Included subanalyses
This analysis includes the following subanalysis:
Allele combinations & result interpretations
Sampling and submission guidelines
References
