DNA & genetic tests
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Deafness with vestibular dysfunction / DVD / DINGS2 (MYO7A-related) - Doberman Pinscher

DNA test for the MYO7A c.3719G>A variant that causes deafness with vestibular dysfunction / DINGS2 in Doberman Pinschers.

Turnaround time
10 workdays
test Methods
Sequencing
Test code
PVT-43A723DF0F05
Species
Dog
Breeds
Doberman Pinscher
Matrices
Blood, Blood (EDTA), Blood (Heparin), Swab, Tissue

Overview

Deafness with vestibular dysfunction in Doberman Pinschers

This genetic test detects the MYO7A c.3719G>A variant that causes deafness with vestibular dysfunction. The condition is also described as DVD, DINGS2, deafness with vestibular dysfunction or an inherited form of deafness with balance problems.

What does this mean for the dog?

MYO7A is important for function of hair cells in the inner ear. Affected puppies can be deaf and show clear vestibular problems, such as head tilt, loss of balance, circling or uncoordinated movement. Signs are often visible early in life.

Practical value of this test

  • Identifies clear dogs, carriers and genetically affected animals.
  • Helps breeders avoid carrier-to-carrier matings.
  • Supports early genetic clarity for deafness and balance problems in Doberman lines.

Inheritance

DVD/DINGS2 caused by this MYO7A variant follows an autosomal recessive inheritance pattern. Two copies cause the disease; one copy makes the dog a carrier.

Included subanalyses

This analysis includes the following subanalysis:

  • Deafness with vestibular dysfunction / DVD / DINGS2 (MYO7A-related) - Doberman Pinscher

Allele combinations & result interpretations

Sampling and submission guidelines

References