Congenital muscular dystrophy / CMD (LAMA2-related) - Italian Greyhound

Congenital muscular dystrophy in Italian Greyhounds

This genetic test assesses the LAMA2 c.3285G>A variant that causes congenital muscular dystrophy in Italian Greyhounds. The condition is also referred to as CMD, congenital muscular dystrophy, MD or LAMA2-related muscular disease.

Affected dogs usually develop clear muscle problems early in life. Typical features include poor growth, generalized muscle atrophy, a stiff or short-strided gait, exercise intolerance, weakness and sometimes regurgitation or poor body condition.

Practical value of this test

• The test clarifies whether a dog is clear, carrier or genetically affected for the tested LAMA2 variant.
• Because the condition is autosomal recessive, carrier combinations are especially important in breeding plans.
• The result helps breeders choose matings more deliberately and avoid puppies with two copies of the variant.