Turnaround time
10 workdays
48.4
40
DNA test for the TBXT c.189C>G variant that causes natural bobtail, brachyury or congenital short tail in dogs.
Overview
This genetic test analyses the TBXT c.189C>G variant in dogs. The trait is also known as tail length, brachyury, T locus, natural bobtail, bobtail or congenital short tail.
TBXT, also known as the T gene, has an important role in embryonic development of the tail and spine. One copy of the variant causes a naturally short or almost absent tail in many breeds. The visible tail length can vary, and other genetic factors may influence how short the tail becomes.
This trait is autosomal dominant. A dog with one copy of the variant usually shows natural bobtail. Two copies of the variant are embryonic lethal and are normally not expected in live puppies.
This test is useful for breeders and owners who want to confirm whether a short tail is explained by the tested TBXT variant. The result also helps avoid matings with an increased risk of embryonic loss from two bobtail alleles.
Included subanalyses
This analysis includes the following subanalysis:
Allele combinations & result interpretations
Below, for each tested locus, you will find the possible allele combinations that may be reported within this analysis, together with a brief explanation of their genetic meaning. The interpretation of possible interactions between different loci is included in the report, but is not shown here in full because that would lead to too many combinations on this page. The final expression may also depend on other genes and their interaction.
Genotype / allele combination: Clear (C/C)
This genotype contains no copy of the tested TBXT bobtail variant. The dog will not pass on this variant, and a short tail, if present, must be explained by another cause.
Genotype / allele combination: Bobtail positive (C/G)
This genotype causes the tested form of natural bobtail. The dog has one copy of the TBXT variant and can pass this bobtail allele to about half of its offspring.
Genotype / allele combination: Homozygous bobtail allele (G/G)
Two copies of this TBXT variant are embryonic lethal. This genotype is normally not expected in live puppies and should be checked very carefully if reported.
Sampling and submission guidelines





References