Shedding / SD locus (MC5R-related) - Dog

SD locus and shedding in dogs

This genetic test detects the MC5R c.709G>A variant at the SD locus. This variant is associated with reduced shedding and shorter coat length in dogs. The test is also described as a shedding test, SD-locus test or MC5R shedding test.

What does this mean for the coat?

MC5R plays a role in the skin and sebaceous glands. Dogs carrying the SD variant tend to shed less than dogs without it. Final coat type is also influenced by other loci, such as hair length and furnishings, so the visible amount of loose hair can differ between dogs.

Practical value of this test

• Helps breeders select more deliberately for shedding level and coat maintenance.
• Gives buyers and owners clearer expectations about the amount of loose hair in the home.
• Is useful in combination with other coat traits, such as hair length, furnishings or wire coat.

Inheritance and result

Shedding is a multifactorial trait. G/G gives the highest MC5R contribution to shedding, G/A indicates one copy of the SD variant and A/A indicates two copies of the variant that lowers the MC5R contribution to shedding.