Turnaround time
10 workdays
48.4
40
DNA test for the MC1R deletion c.439_441del causing russet coat colour in Burmese cats.
Overview
This genetic test detects the MC1R deletion c.439_441del that causes the russet phenotype in Burmese cats. The trait is also described as russet coat colour, russet or an E-locus/MC1R-related colour change. Russet is characterised by a striking warm reddish-brown or apricot-like colour shift that can develop with age.
The variant affects MC1R, a receptor involved in determining which pigment type is expressed in the coat. In genetically russet cats, coat colour can shift toward warmer reddish-brown tones. Final colour still depends on other coat-colour genes, base colour, pattern and age.
Russet is inherited as autosomal recessive: one copy means carrier status, while two copies cause the russet phenotype.
Included subanalyses
This analysis includes the following subanalysis:
Allele combinations & result interpretations
Below, for each tested locus, you will find the possible allele combinations that may be reported within this analysis, together with a brief explanation of their genetic meaning. The interpretation of possible interactions between different loci is included in the report, but is not shown here in full because that would lead to too many combinations on this page. The final expression may also depend on other genes and their interaction.
Genotype / allele combination: Clear
No copy of the tested MC1R variant c.439_441del was detected. This cat will not pass this tested variant to offspring.
Genotype / allele combination: Carrier
This cat carries one copy of the tested MC1R variant c.439_441del. The cat can pass the variant on; visible coat colour depends on the second allele and other coat-colour genes.
Genotype / allele combination: Two copies
This cat has two copies of the tested MC1R variant c.439_441del. This genotype causes russet coat-colour development, with final colour intensity depending on other coat-colour genes.
Sampling and submission guidelines





References