Turnaround time
10 workdays
48.4
40
DNA test for the POMC c.561_575del deletion associated with obesity and increased food motivation in Labrador Retrievers and Flat-Coated Retrievers.
Overview
This genetic test analyses the POMC c.561_575del variant in the Labrador Retriever and Flat-Coated Retriever. The trait is described as obesity, excess body weight, increased food motivation, stronger appetite and POMC-related obesity and food motivation. The test does not measure the dog’s current body weight; it detects an inherited variant that helps explain why some dogs are more food-driven and more prone to weight gain.
Canine obesity is influenced by genetics, diet, activity level, age and daily management. A genetic risk variant can increase predisposition, making a dog more likely to seek food, respond strongly to food rewards or gain weight more easily. For POMC, the result is therefore useful genetic context for weight management and breeding selection.
This test gives breeders, owners and veterinarians useful information to identify dogs with increased inherited predisposition earlier. For breeders, the result supports transparent use of risk variants in selection and mating plans. For owners, it helps tailor feeding, reward use, body-condition monitoring and follow-up to the dog’s individual predisposition.
Obesity predisposition is multifactorial: the tested variant is important, but it is not the only factor determining final body weight. The result shows whether the dog carries zero, one or two copies of the deletie. More risk copies indicate a stronger genetic signal for increased predisposition within the tested variant.
Included subanalyses
This analysis includes the following subanalysis:
Allele combinations & result interpretations
Below, for each tested locus, you will find the possible allele combinations that may be reported within this analysis, together with a brief explanation of their genetic meaning. The interpretation of possible interactions between different loci is included in the report, but is not shown here in full because that would lead to too many combinations on this page. The final expression may also depend on other genes and their interaction.
Genotype / allele combination: No deletion detected (N/N)
This dog does not carry the tested POMC deletion. For this variant, no increased genetic predisposition for extra food motivation or weight gain is detected.
Genotype / allele combination: One copy of the POMC deletion (N/del)
This dog carries one copy of the POMC deletion. This increases the genetic predisposition for food-driven behaviour and weight gain compared with dogs without the deletion.
Genotype / allele combination: Two copies of the POMC deletion (del/del)
This dog carries two copies of the POMC deletion. This gives the strongest genetic signal in this test for increased food motivation and predisposition to gain weight more easily.
Sampling and submission guidelines





References