DNA & genetic tests
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48.4

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40

Muscular hypertrophy / double muscling / Bully Whippet (MSTN-related) - Whippet

DNA test for the MSTN c.939_940delTG variant in Whippets, known for muscular hypertrophy, double muscling, myostatin deficiency and the Bully Whippet phenotype.

Turnaround time
10 workdays
test Methods
Sequencing
Test code
PVT-696BE392B30E
Species
Dog
Breeds
Whippet
Matrices
Blood, Blood (EDTA), Blood (Heparin), Swab, Tissue

Overview

What does this test analyse?

This DNA test analyses the MSTN variant c.939_940delTG in Whippets. The trait is known as muscular hypertrophy, double muscling, myostatin deficiency, hypermuscularity and Bully Whippet syndrome.

What does it mean for the dog?

MSTN encodes myostatin, a negative regulator of muscle growth. The deletion reduces this brake on muscle development. Whippets with one copy often have noticeably increased musculature compared with dogs without the variant. Dogs with two copies develop the pronounced Bully Whippet or double muscling phenotype, with a broad chest, powerful neck and leg muscles and a very muscular build.

  • TG/TG: no tested MSTN deletion.
  • TG/delTG: one copy; usually increased muscularity and important breeding information.
  • delTG/delTG: two copies; causes the clear double muscling phenotype.

Practical value of this test

The result helps Whippet breeders plan muscle development, sport lines and breeding combinations more accurately. It shows which dogs carry the variant, which dogs have two copies and which matings can produce Bully Whippet offspring.

Included subanalyses

This analysis includes the following subanalysis:

  • Muscular hypertrophy / double muscling / Bully Whippet (MSTN-related)

Allele combinations & result interpretations

Sampling and submission guidelines

References