Below, for each tested locus, you will find the possible allele combinations that may be reported within this analysis, together with a brief explanation of their genetic meaning. The interpretation of possible interactions between different loci is included in the report, but is not shown here in full because that would lead to too many combinations on this page. The final expression may also depend on other genes and their interaction.
MDR1 interpretation
Allele combination: No tested MDR1-associated ABCB1 deletion detected
This animal does not carry the tested MDR1-associated ABCB1 deletion. This result therefore does not support the tested variant as an explanation for increased sensitivity to certain medicines. Other medical or genetic factors can still influence drug response.
Allele combination: Carrier of the tested MDR1-associated ABCB1 deletion
This animal carries one copy of the tested MDR1-associated ABCB1 deletion. Even one copy can be associated with increased sensitivity to certain medicines. The result should therefore be taken into account carefully when choosing medication and dosage.
Allele combination: MDR1-associated ABCB1 genotype detected
This animal has the tested MDR1-associated ABCB1 genotype. This genotype is associated with clearly increased sensitivity to certain medicines that depend on P-glycoprotein transport. Medication choice and dosage therefore need extra caution.
