Turnaround time
10 workdays
48.4
40
DNA marker panel for E-locus / extension coat colour in alpacas, assessing three MC1R markers.
Overview
This DNA analysis assesses three MC1R markers at the E-locus, also called the extension locus, in alpacas: MC1R_C901T, MC1R_A82G and MC1R_224-227delACTT. MC1R plays a role in regulating pigment production. The locus is involved in the balance between dark eumelanin and lighter red, yellow or cream pigments.
The result helps breeders include known MC1R markers in colour planning, especially when light, cream, red or darker fibre colours are relevant to a breeding goal. Because alpaca coat colour is influenced by several loci and marker combinations, this analysis reports the tested E-locus markers separately and does not use them alone to predict the full final coat colour.
Included subanalyses
This analysis includes the following subanalyses:
Allele combinations & result interpretations
Below, for each tested locus, you will find the possible allele combinations that may be reported within this analysis, together with a brief explanation of their genetic meaning. The interpretation of possible interactions between different loci is included in the report, but is not shown here in full because that would lead to too many combinations on this page. The final expression may also depend on other genes and their interaction.
Genotype / allele combination: No tested E-locus variant detected
This alpaca has the reference genotype for MC1R_C901T. This specific E-locus variant is not detected, supporting that this marker does not limit dark eumelanin production.
Genotype / allele combination: Carrier of one tested MC1R variant
This alpaca carries one copy of MC1R_C901T. The animal can pass on this E-locus variant. Especially when paired with another animal carrying E-locus variants, this can matter for producing lighter, cream, red or yellowish fibre colours.
Genotype / allele combination: Homozygous positive for the tested MC1R variant
This alpaca is homozygous positive for MC1R_C901T. This is a clear E-locus result consistent with reduced dark eumelanin production and a shift toward lighter, cream, red or yellowish fibre colour. Dark A-locus patterns can become less visible as a result.
Genotype / allele combination: No tested E-locus variant detected
This alpaca has the reference genotype for MC1R_A82G. This specific E-locus variant is not detected, so this marker gives no indication of a shift toward lighter fibre colour.
Genotype / allele combination: Carrier of one tested MC1R variant
This alpaca carries one copy of MC1R_A82G. The animal is a carrier and can pass on this variant. This is valuable for breeding plans because combinations of E-locus variants can shift the balance between dark pigment and lighter red, yellow or cream pigmentation.
Genotype / allele combination: Homozygous positive for the tested MC1R variant
This alpaca is homozygous positive for MC1R_A82G. This gives a clear E-locus indication of a lighter pigment direction, with less emphasis on dark eumelanin and greater potential for red, yellow or cream fibre expression. It can mask black or dark A-locus potential.
Genotype / allele combination: No tested E-locus variant detected
This alpaca has no copy of the tested MC1R_224-227delACTT deletion. This specific E-locus deletion is therefore not detected; for this marker, dark pigment remains genetically possible when supported by other loci.
Genotype / allele combination: Carrier of one tested MC1R variant
This alpaca carries one copy of the MC1R_224-227delACTT deletion. The animal can pass on this E-locus deletion. When combined with another E-locus variant, this can matter for lighter, cream, red or yellowish fibre colours and for limiting dark pigment expression.
Genotype / allele combination: Homozygous positive for the tested MC1R variant
This alpaca is homozygous positive for the MC1R_224-227delACTT deletion. This is a strong E-locus result for limiting dark pigment and shifting toward lighter, cream, red or yellowish fibre colour. With this result, a dark A-locus result can be largely hidden in the visible coat.
Sampling and submission guidelines




Collect the sample cleanly, avoid cross-contamination between animals, and allow swabs to dry completely before shipment.
References