DNA & genetic tests
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48.4

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40

Coat colour white spotting / roan-ticked / piebald (KIT/USH2A/MITF) - Dog

Panel for three canine white-pattern coat traits: Panda white spotting, roan/ticked and piebald through KIT, USH2A and MITF.

Turnaround time
10 workdays
test Methods
Sequencing
Test code
PVT-B3C0451EFB43
Species
Dog
Matrices
Blood, Blood (EDTA), Blood (Heparin), Swab, Tissue

Overview

What does this panel test?

This canine coat-colour DNA test combines three markers that are important for white-pattern traits. The panel tests KIT for Panda white spotting, USH2A for roan/ticked patterns and MITF for piebald or parti-colour through the S-locus. Together, these markers help explain different ways in which white areas, pigmented speckling and irregular white patches can appear in a dog’s coat.

The test is useful because the visible coat does not always tell the full genetic story. A dog may show a pattern clearly, show it only subtly, or pass a relevant allele to offspring. Base colour, breed background and other coat-colour loci can also influence the final appearance, so DNA information gives breeders a stronger basis for planning matings and setting realistic expectations for puppies.

Names used for these patterns

  • Panda white spotting is mainly used for the KIT-related pattern in German Shepherd Dogs, with distinctive white markings on areas such as the head, chest, feet and tail.
  • Roan and ticked describe pigment appearing in white coat areas. Ticked coats show separate spots; roan coats show a more even mixture of white and pigmented hairs.
  • Piebald, parti, particoloured, random white and S-locus are used for MITF-related white patterning that can range from small markings to very extensive white areas.

Practical value of this test

  • Helps breeders plan more deliberately when white markings, roan/ticking or piebald patterning are desired or should be managed carefully.
  • Shows whether a dog can pass on a tested marker, even when the visible pattern is limited or modified by other coat-colour genes.
  • Supports interpretation of litters with white puppies, speckled puppies or unexpected variation in coat pattern.
  • Improves mating and selection decisions because some white patterns can become stronger depending on allele dosage and genetic background.

Interpretation nuance

White-pattern traits are often more complex than a single result. Roan and ticking are mainly visible in white coat areas; piebald inheritance can differ between breeds; and the Panda variant is described as a dominant pattern for which live dogs with two copies are not expected. A negative result does not rule out every possible cause of white markings, but it does clarify the status of the markers included in this panel.

Included subanalyses

This analysis includes the following subanalyses:

  • Panda white spotting (KIT c.140_141insA) - German Shepherd Dog
  • Piebald / parti S-locus (MITF-related) - Dog
  • Roan / ticked T-locus (USH2A-related) - Dog

Allele combinations & result interpretations

Sampling and submission guidelines

References