Below, for each tested locus, you will find the possible allele combinations that may be reported within this analysis, together with a brief explanation of their genetic meaning. The interpretation of possible interactions between different loci is included in the report, but is not shown here in full because that would lead to too many combinations on this page. The final expression may also depend on other genes and their interaction.
E locus e1 / recessive red/yellow (MC1R c.916C>T) - Dog
Genotype / allele combination: No e1 (C/C)
The tested e1 variant was not detected. This dog will not pass on this specific E-locus allele.
Genotype / allele combination: e1 present (C/T)
The dog carries one copy of e1. This does not by itself cause recessive recessive red/yellow, but it is important because it can combine with a second recessive e allele in offspring.
Genotype / allele combination: e1/e1 (T/T)
The dog has two copies of e1. For this marker, this causes the recessive recessive red/yellow direction; other coat-colour genes can still influence the final shade.
E locus e2 / cream/light red-yellow (MC1R c.-432G>C) - Dog
Genotype / allele combination: No e2 (G/G)
The tested e2 variant was not detected. This dog will not pass on this specific E-locus allele.
Genotype / allele combination: e2 present (G/C)
The dog carries one copy of e2. This does not by itself cause recessive cream/light red-yellow, but it is important because it can combine with a second recessive e allele in offspring.
Genotype / allele combination: e2/e2 (C/C)
The dog has two copies of e2. For this marker, this causes the recessive cream/light red-yellow direction; other coat-colour genes can still influence the final shade.
E locus e3 / pale yellow/white (MC1R c.816_817del) - Dog
Genotype / allele combination: No e3 (N/N)
The tested e3 variant was not detected. This dog will not pass on this specific E-locus allele.
Genotype / allele combination: e3 present (N/del)
The dog carries one copy of e3. This does not by itself cause recessive pale yellow/white, but it is important because it can combine with a second recessive e allele in offspring.
Genotype / allele combination: e3/e3 (del/del)
The dog has two copies of e3. For this marker, this causes the recessive pale yellow/white direction; other coat-colour genes can still influence the final shade.
E locus Em / melanistic mask (MC1R c.790A>G) - Dog
Genotype / allele combination: No Em (A/A)
The tested Em variant was not detected. This dog will not pass on this specific E-locus allele.
Genotype / allele combination: Em present (A/G)
The dog carries one copy of Em. This allele can cause melanistic mask when the other coat-colour genes make the pattern visible.
Genotype / allele combination: Em/Em (G/G)
The dog has two copies of Em. This strengthens the genetic presence of this E-locus allele and can pass melanistic mask clearly to offspring.
E locus Eg / grizzle/domino (MC1R c.233G>T) - Dog
Genotype / allele combination: No Eg (G/G)
The tested Eg variant was not detected. This dog will not pass on this specific E-locus allele.
Genotype / allele combination: Eg present (G/T)
The dog carries one copy of Eg. This allele can cause grizzle/domino when the other coat-colour genes make the pattern visible.
Genotype / allele combination: Eg/Eg (T/T)
The dog has two copies of Eg. This strengthens the genetic presence of this E-locus allele and can pass grizzle/domino clearly to offspring.
E locus eH / sable (MC1R c.250G>A) - Dog
Genotype / allele combination: No eH (G/G)
The tested eH variant was not detected. This dog will not pass on this specific E-locus allele.
Genotype / allele combination: eH present (G/A)
The dog carries one copy of eH. This allele can cause sable when the other coat-colour genes make the pattern visible.
Genotype / allele combination: eH/eH (A/A)
The dog has two copies of eH. This strengthens the genetic presence of this E-locus allele and can pass sable clearly to offspring.
