Turnaround time
10 workdays
48.4
40
DNA test for classic grey / dominant white in alpacas, with analysis of KIT.
Overview
This genetic test examines the KIT variant c.376G>A associated with classic grey. Classic grey is not a single flat grey colour, but a colour and pattern factor that can lighten the alpaca’s base coat colour and produce white or strongly diluted areas.
Expression can vary considerably. Some alpacas show a clear classic-grey pattern with a white face, lighter legs and multiple colour tones within the fibre. Other animals are minimally or cryptically grey, making them difficult to distinguish visually from animals with white spotting, a light base colour or other coat-colour patterns.
The variant follows autosomal dominant inheritance. One copy can be sufficient to produce classic grey, although visibility still depends on base colour and other colour or spotting factors. Two copies are considered probably embryonic lethal, so living homozygous animals are not or hardly expected.
The result helps breeders genetically distinguish alpacas with and without the KIT grey factor. This is especially valuable for unclear or light colours, cryptic animals and breeding plans where matings between two classic-grey animals should be deliberately avoided. The test also supports the distinction between classic grey and other white or dilution patterns that may look similar but have a different genetic basis.
Included subanalyses
This analysis includes the following subanalysis:
Allele combinations & result interpretations
Below, for each tested locus, you will find the possible allele combinations that may be reported within this analysis, together with a brief explanation of their genetic meaning. The interpretation of possible interactions between different loci is included in the report, but is not shown here in full because that would lead to too many combinations on this page. The final expression may also depend on other genes and their interaction.
Genotype / allele combination: No tested KIT grey factor detected
The alpaca does not carry the tested KIT c.376G>A variant. This is consistent with absence of the classic grey factor for this variant.
Genotype / allele combination: One copy of the KIT grey factor
The alpaca carries one copy of the KIT c.376G>A variant. This genotype is associated with classic grey; visibility can depend on base colour and other colour or spotting factors.
Genotype / allele combination: Two copies of the KIT grey factor
The alpaca has two copies of the KIT c.376G>A variant. Two copies are described as probably embryonic lethal; a live homozygous result is therefore unusual and requires careful assessment.
Sampling and submission guidelines




References